https://jiomics.com/index.php/jiomics/issue/feedJournal of Integrated OMICS2025-06-12T14:28:50+00:00Jose Luis Capelo Martínezjlcapelom@proteomass.orgOpen Journal Systems<div class="mainrow"> <div class="homeImageMini">JIOMICS provides a forum for the publication of original research papers, letters to the editor, short communications, and critical reviews in all branches of pure and applied –omics subjects, such as proteomics, metabolomics, metallomics and genomics. Especial interest is given to papers where more than one –omics subject is covered. Papers are evaluated based on scientific novelty and demonstrated scientific applicability. Original research papers on fundamental studies, and novel sensor and instrumentation development, are especially encouraged. Novel or improved findings in areas such as clinical, medicinal, biological, environmental and materials –omics are welcome.</div> <div class="homeImageMini"> <div class="homeImageMini"> </div> <div class="homeDescription"> <table style="height: 144px; width: 100%; border-collapse: collapse;" border="0"> <tbody> <tr style="height: 18px;"> <td style="width: 50%; height: 18px;"><a href="https://www.jiomics.com/index.php/jiomics/issue/current">Current Issue</a></td> <td style="width: 50%; height: 18px; text-align: right;"><a href="https://www.jiomics.com/index.php/jiomics/issue/archive">Previous issues</a></td> </tr> <tr style="height: 18px;"> <td style="width: 50%; height: 18px;"><a href="https://www.jiomics.com/index.php/jiomics/issue/archive">Accepted manuscripts</a></td> <td style="width: 50%; height: 18px; text-align: right;"><a href="https://www.jiomics.com/index.php/jiomics/about">Editorial Board</a></td> </tr> <tr style="height: 18px;"> <td style="width: 50%; height: 18px;"><a href="https://www.jiomics.com/index.php/jiomics/about/submissions#onlinesubmissions">Guide for authors</a></td> <td style="width: 50%; height: 18px; text-align: right;"><a href="https://www.jiomics.com/index.php/jiomics/about/submissions#templateforonlinesubmissions">Template for submissions</a></td> </tr> <tr style="height: 18px;"> <td style="width: 50%; height: 18px;"><a href="https://www.jiomics.com/index.php/jiomics/about/submissions#templateforonlinesubmissions">JIOMICS references format</a></td> <td style="width: 50%; height: 18px; text-align: right;"><a href="https://www.jiomics.com/index.php/jiomics/about/submissions#authorfees">Fees</a></td> </tr> </tbody> </table> </div> </div> </div>https://jiomics.com/index.php/jiomics/article/view/239A study of SARS-CoV-2 genomic profiles, evolutionary changes, and transmission dynamics in Southeastern India during three pandemic waves2025-02-14T06:24:35+00:00Vanathy Kvanathyk1@gmail.comAgieshkumar Balakrishna Pillaiagiesh.b@gmail.comVignesh Mariappanvigneshvickey585@rocketmail.comMalarvizhi Ramalingam malarvizhimanju@gmail.comPajanivel Raganadinpajanivelr@mgmcri.ac.inRamya Ramadossramyar@mgmari.sbvu.ac.inBalasubramanian Moovarkumudalvanbalam@mgmari.sbvu.ac.inJoshy M Easowjoshymeasow@mgmcri.ac.inMadavan Vasudevanmadavan@theomics.comS.R. Raoraghudbt@gmail.com<p style="font-weight: 400;">SARS-CoV-2 bio-surveillance at all levels is crucial for understanding its genetic evolution and vaccine effectiveness.This study investigated the emergence and evolution of new SARS-CoV-2 variants in the city of Puducherry, India throughout the three peaks of infection. A total of 128 samples were subjected to Illumina deep RNA sequencing. The results indicate that the first wave was dominated by uncommon variants, the second by Delta, and the third by Omicron. Lineages B.1.560 and B.1.617.2 were most prevalent. Analysis of 3133 common and 11 new mutations revealed Spike_D614G as the most common mutation and a novel set of mutations was observed in NS16, a key immune evasion factor. These NS16 mutations raise concerns about increased virulence, reduced vaccine efficacy, and potential antiviral resistance, warranting further investigation. Our findings contribute to SARS-CoV-2 evolutionary and genetic epidemiology research and highlight the need for ongoing surveillance to anticipate future variant threats.</p>2025-06-12T00:00:00+00:00Copyright (c) 2025 Journal of Integrated OMICShttps://jiomics.com/index.php/jiomics/article/view/244Vol 15 No 2 (2025)2025-06-12T14:09:04+00:00José Luís Capelo Martínezjlcapelom@bioscopegroup.org2025-06-12T00:00:00+00:00Copyright (c) 2025 Journal of Integrated OMICShttps://jiomics.com/index.php/jiomics/article/view/246Overcoming Barriers to Personalized Medicine2025-06-02T09:16:22+00:00Carlos Lodeirocle@fct.unl.ptJosé Luís Capelo Martínezjlcapelom@bioscopegroup.orgFederica Pelattifederica.pellati@unimore.itDaphné Choparddaphne.chopard@inf.ethz.chLena Voith von Voithenberglena.voithenberg@dkfz-heidelberg.deNir Peledpeled.nir@gmail.comGianluca Moroncinig.moroncini@univpm.itLaura Mercolinilaura.mercolini@unibo.itCristina Zibettizibettic@gmail.comTian-Li Wangtlwang21212@yahoo.comTânia Moraistsmorais@ciencias.ulisboa.ptGamze Gürsoyggursoy@nygenome.orgDaniele Lo Relore.daniele.mail@gmail.comLuís Perpétuoluisperpetuo@ua.ptErica Quagliarinierica.quagliarini@uniroma1.itRong Fanrong.fan@yale.eduRossella De Marcorossella.demarco@uniud.itLeandro Teodoro Júniorteoolt.bio@usp.brStavroula Baritakibaritaks@uoc.grMichael Shermansherma1@ariel.ac.ilAnna Bielecka Wajdmanbielecka.wajdman@gmail.comMarco Tutonemarco.tutone@unipa.itVarum Kumar Nomulavarunkits@gmail.comSobia Noreensobia.noreen3@unibo.it2025-06-12T00:00:00+00:00Copyright (c) 2025 Journal of Integrated OMICS