https://jiomics.com/index.php/jiomics <div class="mainrow"> <div class="homeImageMini">JIOMICS provides a forum for the publication of original research papers, letters to the editor, short communications, and critical reviews in all branches of pure and applied –omics subjects, such as proteomics, metabolomics, metallomics and genomics. Especial interest is given to papers where more than one –omics subject is covered. Papers are evaluated based on scientific novelty and demonstrated scientific applicability. Original research papers on fundamental studies, and novel sensor and instrumentation development, are especially encouraged. Novel or improved findings in areas such as clinical, medicinal, biological, environmental and materials –omics are welcome.</div> <div class="homeImageMini"> <div class="homeImageMini"> </div> <div class="homeDescription"> <table style="height: 144px; width: 100%; border-collapse: collapse;" border="0"> <tbody> <tr style="height: 18px;"> <td style="width: 50%; height: 18px;"><a href="https://www.jiomics.com/index.php/jiomics/issue/current">Current Issue</a></td> <td style="width: 50%; height: 18px; text-align: right;"><a href="https://www.jiomics.com/index.php/jiomics/issue/archive">Previous issues</a></td> </tr> <tr style="height: 18px;"> <td style="width: 50%; height: 18px;"><a href="https://www.jiomics.com/index.php/jiomics/issue/archive">Accepted manuscripts</a></td> <td style="width: 50%; height: 18px; text-align: right;"><a href="https://www.jiomics.com/index.php/jiomics/about">Editorial Board</a></td> </tr> <tr style="height: 18px;"> <td style="width: 50%; height: 18px;"><a href="https://www.jiomics.com/index.php/jiomics/about/submissions#onlinesubmissions">Guide for authors</a></td> <td style="width: 50%; height: 18px; text-align: right;"><a href="https://www.jiomics.com/index.php/jiomics/about/submissions#templateforonlinesubmissions">Template for submissions</a></td> </tr> <tr style="height: 18px;"> <td style="width: 50%; height: 18px;"><a href="https://www.jiomics.com/index.php/jiomics/about/submissions#templateforonlinesubmissions">JIOMICS references format</a></td> <td style="width: 50%; height: 18px; text-align: right;"><a href="https://www.jiomics.com/index.php/jiomics/about/submissions#authorfees">Fees</a></td> </tr> </tbody> </table> </div> </div> </div> Proteomass en-US Journal of Integrated OMICS 2182-0287 https://jiomics.com/index.php/jiomics/article/view/251 <p class="p1">Blood is one of the most informative biological traces recovered from crime scenes. Beyond conventional DNA profiling, its proteome may provide contextual information concerning when a stain was deposited and broad biological characteristics of the donor. This critical review examines three interconnected applications of forensic blood proteomics: time since deposition estimation, biological-age estimation and biological-sex estimation. We evaluate evidence from haemoglobin oxidation, plasma ageing signatures and sex-associated proteins; examine environmental, substrate and donor-related confounders; and compare the statistical and machine-learning approaches used for prediction. Six proteins, ITIHS, HSPA9, SNAP91, FIL, XPO4 and NCF2, currently provide the strongest replicated feature-selection evidence for age association in dried bloodstains. We further propose a nanoLC-timsTOF diaPASEF workflow for future validation, combining trapped-ion mobility, rigorous quality control, and multi-output models to simultaneously estimate several forensic attributes. Although a unified assay has not yet been validated in a single representative bloodstain cohort, the available evidence supports further development of proteomics as a complement to DNA profiling for crime-scene reconstruction.</p> Raquel Fonseca Inês F. Domingos Hugo M. Santos José Luís Capelo Martínez Copyright (c) 2026 Journal of Integrated OMICS https://creativecommons.org/licenses/by/4.0 2026-07-31 2026-07-31 16 1 1 12 10.5584/jiomics.v16i1.251