Multiparametric analysis of crystallogenic properties of blood serum of healthy people and patients with burn disease

DOI: 10.5584/jiomics.v10i2.329

Abstract

The aim of the study was to assess some of the biophysical properties of dehydrated biological fluids in patients with thermal trauma. Own and initiated by the basic substance (0.9% sodium chloride solution) crystallization of blood serum of 32 patients with burn disease (contact burn, the area of skin lesions - 15-45% of the body surface; acute toxemia phase; age 21-40 years), as well as 30 healthy people of comparable age were studied. It is shown that in thermal injury undergo significant changes all outcome measures of biocrystalloscopic and impedance parameters in relation to their own and initiated the crystallogenesis of the blood serum. These changes are manifested in both time and quality parameters. Thus, burn disease in the stage of acute toxemia is characterized by slowing and inhibition of dehydration structuring of samples, increased degree of destruction of the formed elements, relative narrowing of the boundary zone, etc., which is confirmed by the data of registration of acoustic impedance. Based on these results, it is assumed that the visualization and study of the impedance characteristics of the dynamics of drying of serum droplets can be a convenient tool for diagnosing the patient's condition in combustiology.